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PKCalpha Antibody

Protein Kinase C alpha Antibody

Catalog No. Product Name Size List Price (US$) Quantity
PA000229-R12-3330 PKCA Polyclonal Antibody 50 ug 250.00
PA000229-R12-3330 PKCA Polyclonal Antibody 100 ug 350.00
Description

Background
Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (?, ?I, ?II and?) and novel (n) PKC isoforms (?,?,?,?and?). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC and are independent of Ca2+ On the other hand, nPKC and , as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.

PA000229-R12-3330: PKCα Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: PKCα Antibody detects endogenous levels of PKCα.
Applications: WB: 1:500~1:1000; ELISA: 1:10000.
Reactivity: Human, Mouse, Rat.
Immunogen: The antiserum was produced against synthesized peptide derived from human PKCα.
Purification: The antibody was affinity-purified from rabbit anti-serum by immunogenic peptide affinity-chromatography.
Form of Antibody: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Other PKC alpha Antibodys:
PKCα Polyclonal Antibody

PKC alpha Enzyme:
Recombinant Human PKCα

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