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Background Information:
PF-06855800 (PF06855800) is a clinical-stage, SAM-pocket-binding (SAM competitive) PRMT5 inhibitor with high selectivity and affinity (PRMT5-MEP-50, Ki < 0.1 nM) and demonstrates robust and efficacious antiproliferative activity in both in vitro and in vivo models.
APIM050061: PF-06855800 (PF06855800)
CAS No.: 1989620-04-3.
Molecular Formula: C17H16ClFN4O4?H2O.
Molecular Weight: 412.8 (or refer to the Certificate of Analysis, batch-specific).
Purity: >99% chemically and stereomerically pure (by achiral and chiral HPLCs).
QC: Achiral and Chiral HPLCs, MS, NMR, and Elemental Analysis Report.
Solubility: Refer to Certificate of Analysis.
Storage: Refer to Certificate of Analysis.
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