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PEG4/PFB Long Chain Crosslinker

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Description
Peg4/PFB, is an extended hydrophilic linker analog of S-4FB. This linker reacts with primary amines on biomolecules and converts them to 4-formylbenzamide (4FB) moieties with an extended PEG4 linker. 4FB/PEG4-modified proteins are more water-soluble (less hydrophobic) than 4FB-modified proteins, which can eliminate precipitation issues with certain proteins. The extended PEG linker enhances solubility and reduces steric hindrance leading to increased in conjugate yield.
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