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Background Information:
A potent and highly selective cyclindependent kinase 4 and 6 (CDK 4/6) with IC50 at 11 and 16 nM, respectively. Palbociclib Isethionate salt is the clinical formulation format in clinical trials.
APIM050218: PALBOCICLIB (PD-0332991) (ISETHIONATE SALT)
CAS No.: 827022-33-3.
Molecular Formula: C24H29N7O2 ?1.2 C2H6O4S?0.5H2O.
Molecular Weight: 607.4.
Purity: >99% (HPLC at 214 and 254 nm).
QC: HPLC, MS, 1HNMR.
Solubility: Soluble in DMSO, Ethanol and Water.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
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