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Home > Proteins & Peptides > A-Z Proteins  > PAK4KD Enzyme

PAK4KD Enzyme

PAK4 Kinase Domain

Catalog No. Product Name Size List Price (US$) Quantity
BP001575-K0107 Recombinant Human PAK4 kinase domain Enzyme 10 ug 340.00
BP001575-K0107 Recombinant Human PAK4 kinase domain Enzyme 100 ug 2500.00
BP001575-K0107 Recombinant Human PAK4 kinase domain Enzyme 1 mg 8000.00
Description

Introduction

Human PAK4 kinase (UniProt: O96013; NCBI: NM_005884) belongs to a family of p21-activated kinases. These serine/threonine kinases are regulated by the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.

BP001575-K0107: Recombinant Human PAK4 Kinase Domain (PAK4KD) Enzyme

Source: E. coli-derived.
Predicted molecular mass: 33,309 Da. PAK4KD is fully phosphorylated at S474 with a measured mass of 33,389 (1P).
Specific activity: 5,595 pmoles/min/ug. Analysis of enzymatic activity was performed according to the Zlyte assay protocol (Invitrogen).
Formulation: 1 ug/ml in Storage Buffer of 25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10% glycerol, 5 mM DTT.
Applications: Enzymatic studies, inhibitor screen, and selectivity profiling; High concentration available for crystallization.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

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