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OBFC1 Protein

Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, STN1, CST Complex Subunit STN1

Catalog No. Product Name Size List Price (US$) Quantity
BP002636-CF99 Recombinant Human OBFC1 Protein 10 ug 180.00
BP002636-CF99 Recombinant Human OBFC1 Protein 50 ug 528.00
BP002636-CF99 Recombinant Human OBFC1 Protein 1 mg 2880.00
Description

Introduction
CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.

BP002636-CF99: Recombinant Human Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1 (OBFC1)

Source: E. coli-derived.
Recombinant Human Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1 (OBFC1) is expressed with sequence (Met1-Phe368) of Human OBFC1 fused with a His tag at the N-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: 0.2 um filtered solution of 20 mM Tris, 1 mM DTT, pH 8.0.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

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