My Cart [ 0 ]
Home > Chemicals > Inhibitors, Activators, Antagonists, and Agonists > A-Z Inhibitors, Activators, Antagonists, and Agonists > NVP-TAE684

NVP-TAE684

TAE684

Catalog No. Product Name Size List Price (US$) Quantity
APIM050211 NVP-TAE684 5 mg 100.00
APIM050211 NVP-TAE684 10 mg 130.00
APIM050211 NVP-TAE684 50mg 350.00
APIM050211 NVP-TAE684 100 mg 500.00
APIM050211 NVP-TAE684 200 mg 800.00
Description

Background Information:

A potent, selective and efficacious inhibitor of NPM-ALK.

Reference:

1. Galkin, A. V., et al., Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK., Proc Natl Acad Sci USA, 2007, 104 (1), 270-275.
2. McDermott, U., et al., Genomic Alterations of Anaplastic Lymphoma Kinase May Sensitize Tumors to Anaplastic Lymphoma Kinase Inhibitors, Cancer Res, 2008, 68(9), 3389-3395.

APIM050211: NVP-TAE684

CAS No.: 761439-42-3.
Molecular Formula: C30H40ClN7O3S.
Molecular Weight: 614.22.
Purity: >99% (HPLC at 214 and 254 nm).
QC: MS, HPLC and 1HNMR.
Solubility:Soluble in DMSO and water with 2 eq. of acid.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.

Related Links

See our Privacy Policy