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Background Information:
A potent and specific inhibitor of heat shock protein Hsp90a/b with IC50 of 13 and 21 nM, respectively.
Reference:
1. Brough, P. A., et al, 4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer, J. Med. Chem, 2008, 51 (2), 196–218.
APIM050351: NVP-AUY922
CAS No.: 747412-49-3.
Molecular Formula: C26H31N3O5.
Molecular Weight: 465.54.
Purity: 99% (HPLC at 214 and 254 nm).
QC: LC/MS, 1HNMR.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
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