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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal Notch 1 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Background
Notch proteins are single-pass transmembrane receptors that regulate cell fate decisions during development. The Notch family includes 4 receptors, NOTCH1, NOTCH2, NOTCH3, and NOTCH4, whose ligands include JAG1, JAG2, DLL1), DLL3, and DLL4. Notch homolog 1, translocation-associated (NOTCH1), is a human gene encoding a single-pass transmembrane receptor.It functions as a receptor for membrane bound ligands, and may play multiple roles during development.NOTCH1 may normally coordinates the process of somitogenesis,1 and the activated Notch 1 and Notch 3 promote ifferentiation of progenitor cells into astroglia.2.
PA000211-PA1215: NOTCH1 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human. No cross reactivity with other proteins.
Applications: WB 1 ug/ml.
Reactivity: Human.
Immunogen: A synthetic peptide corresponding to a sequence at the middle region of human NOTCH1, different from the related rat sequence by one amino acid.
Purification: Immunogen affinity purified.
Form of Antibody: 0.2ml of distilled water will yield a concentration of 500?g/ml.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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