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Notch 1 Antibody

neurogenic locus notch 1; NOTC1; notch 1 (translocation-associated); Notch homolog 1

Catalog No. Product Name Size List Price (US$) Quantity
PA000211-PA1215 NOTCH1 Polyclonal Antibody 100 ug 350.00
Description

Background

Notch proteins are single-pass transmembrane receptors that regulate cell fate decisions during development. The Notch family includes 4 receptors, NOTCH1, NOTCH2, NOTCH3, and NOTCH4, whose ligands include JAG1, JAG2, DLL1), DLL3, and DLL4. Notch homolog 1, translocation-associated (NOTCH1), is a human gene encoding a single-pass transmembrane receptor.It functions as a receptor for membrane bound ligands, and may play multiple roles during development.NOTCH1 may normally coordinates the process of somitogenesis,1 and the activated Notch 1 and Notch 3 promote ifferentiation of progenitor cells into astroglia.2.

PA000211-PA1215: NOTCH1 Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human. No cross reactivity with other proteins.
Applications: WB 1 ug/ml.
Reactivity: Human.
Immunogen: A synthetic peptide corresponding to a sequence at the middle region of human NOTCH1, different from the related rat sequence by one amino acid.
Purification: Immunogen affinity purified.
Form of Antibody: 0.2ml of distilled water will yield a concentration of 500?g/ml.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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