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Conditions of optimal MINPP1 Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Multiple inositol polyphosphate phosphatase 1, also known as Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase, is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 aa precursor that contains an 30 aa signal peptide and a 457 aa mature chain. MINPP1 widely expressed with highest levels in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).
BP001321-C525: Recombinant Human Multiple Inositol Polyphosphate Phosphatase 1 (MINPP1) Enzyme
Source: HEK 293 cell-derived.
Recombinant Human Multiple Inositol Polyphosphate Phosphatase 1 (MINPP1) Enzyme is a secreted protein with sequence (Ser31-Leu487) of Human MINPP1 fused with a polyhistidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 EU/ug).
Formulation: 0.2 um filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH 7.5.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
MINPP1 Antibodies:
MINPP1 Polyclonal Antibody
MINPP1 Polyclonal Antibody
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