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MCP-1 Antibody

MCP-1/CCL2 Antibody

Catalog No. Product Name Size List Price (US$) Quantity
PA004038-PA1356 MCP-1 Polyclonal Antibody 100 ug 350.00
Description

Background
Monocyte chemoattractant protein-1 (MCP-1), a member of the chemokine (chemotactic cytokine) family, is a potent monocyte agonist that is upregulated by oxidized lipids.1 MCP-1 is also known as CCL2, SCYA2, MCAF. MCAF is a member of family of factors involved in immune and inflammatory responses. The amino acid sequence deduced from the nucleotide sequence reveals the primary structure of the MCAF precursor to be composed of a putative signal peptide sequence of 23 amino acid residues and a mature MCAF sequence of 76 amino acid residues.2 MCP-1 plays a unique and crucial role in the initiation of atherosclerosis and may provide a new therapeutic target in this disorder.3 Human MCP-1 is a 8.7KDa non-glycoprotein, consisting of 99 amino acids in precursor form and 76 amino acids in mature form.

PA004038-PA1356: MCP-1 Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human, rat, mouse. No cross reactivity with other proteins.
Applications: WB 1 ug/ml.
Reactivity: Human, Rat, Mouse.
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human MCP-1 (24-36 aa), different from the mouse sequence by two amino acids.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

MCP 1 Proteins:
Recombinant Rat MCP-1 (CCL2)
Recombinant Mouse MCP-1 (CCL2)
Recombinant Human MCP-1 (CCL2), His Tag
Recombinant Human MCP-1 (CCL2)

MCP-1 ELISA Kits:
Mouse MCP-1 ELISA Kit
Human MCP-1 ELISA Kit

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