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Conditions of optimal LRRTM2 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Introduction
Leucine-rich repeat transmembrane neuronal protein 2, also known as Leucine-rich repeat neuronal 2 protein, KIAA0416, LRRN2 and LRRTM2, is a Single-pass type I membrane protein which Belongs to the LRRTM family. It contains 10 LRR (leucine-rich) repeats, 1 LRRCT domain, and 1 LRRNT domain. LRRTM2 is expressed in neuronal tissues, and Interacts with DLG4 and NRXN1. LRRTM2 has been suggested to involve in the development and maintenance of excitatory synapse in the vertebrate nervous system. LRRTM2 also regulates surface expression of AMPA receptors. LRRTM2 acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B.
BP001354-C618: Recombinant Human Leucine-rich repeat transmembrane neuronal protein 2 (LRRTM2) Protein
Source: HEK 293-derived.
Recombinant Human Leucine-rich repeat transmembrane neuronal protein 2 (LRRTM2) Protein is expressed with sequence (Cys34-Arg422) of Human LRRTM2 fused with a polyhistidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 EU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
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