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LIR-1 Protein

Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1, MIR-7, CD85j, ILT-2, CD85 Antigen-Like Family Member J

Catalog No. Product Name Size List Price (US$) Quantity
BP001388-C484 Recombinant Human LIR-1 Protein 50 ug 252.00
BP001388-C484 Recombinant Human LIR-1 Protein 1 mg 2640.00
BP001388-C484 Recombinant Human LIR-1 Protein 10 ug 98.00
Description

Introduction
The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors(LIR) and monocyte/macrophage Ig-like receptors (MIR)) canactivating and inhibitory immunoreceptors. ILT expressed on many leukocyte subsets and regulaedt of immune responses. ILTs share significant homology with killer cell Ig-like receptors (KIR). Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains. ILT2 (also known as LIR1, MIR7, and CD85j) is expressed on most monocytes, dendritic cells, and mature B cells. ILT2 is also expressed on smallPercentages of T cells and NK cells. ILT2 can prevents cellular activation.

BP001388-C484: Recombinant Human Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 (LIR-1) Protein

Source: HEK 293-derived.
Recombinant Human Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 (LIR-1) Protein is a secreted protein with sequence (Gly24-His458) of Human LILRB1 fused with a polyhistidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

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