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IRF5 Protein

Interferon Regulatory Factor 5, IRF-5

Catalog No. Product Name Size List Price (US$) Quantity
BP002605-CF18 Recombinant Human IRF5 Protein 10 ug 180.00
BP002605-CF18 Recombinant Human IRF5 Protein 50 ug 528.00
BP002605-CF18 Recombinant Human IRF5 Protein 1 mg 2880.00
Description

Introduction
Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis.

BP002605-CF18: Recombinant Human Interferon Regulatory Factor 5 (IRF5) Protein

Source: E. coli-derived.
Recombinant Human Interferon Regulatory Factor 5 (IRF5) Protein is expressed with sequence (Met1-Gln498) of Human IRF5 fused with a 6His tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: 0.2 um filtered solution of PBS, pH 7.4.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

IRF5 Antibodies:
IRF5 Monoclonal Antibody

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