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Conditions of optimal IL-31RB Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Oncostatin-M-specific receptor subunit beta (OSMR?) is a 150-180 kDa member of the IL-6receptor family. OSMR? associates with gp130 to form the type II OSM receptor ,the receptor is responsive to OSM. Gp130 subunit is shared by other IL-6 family cytokine receptors, and OSMR? associates with gp130-like receptor (GPL) to form areceptor complex responsive to IL-31. The human OSMR? cDNA encodes a 979 amino acid (aa) precursor, the precursor includes a 27 aa signal sequence, a 712 aa extracellular domain (ECD), a 22 aatransmembrane segment, and a 218 aa cytoplasmicdomain. The ECD contains one partial and one complete hematopoietin domain, an Ig-like domain,and three fibronectin type-III domains.
BP001386-C496: Recombinant Human Interleukin-31 receptor subunit beta (IL-31RB) Protein
Source: HEK 293-derived.
Recombinant Human Interleukin-31 receptor subunit beta (IL-31RB) Protein is a secreted protein with sequence (Glu28-Ser739) of Human OSMRB fused with a polyhistidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
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