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Conditions of optimal IFN-gamma antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Description
Interferon-γ (IFN-γ) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-gamma strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB.
PA000576-Mab-604010: IFN-γ Monoclonal Antibody
Mouse Monoclonal Antibody.
Applications: nti-IFN-? recognizes recombinant IFN-γ by Western Blot and ELISA.
Reactivity: Human.
Immunogen: Ni-NTA purified recombinant human IFN-γ expressed in E. Coli strain BL21 (DE3).
Form of Antibody: Antibodies are purified by protein A affinity chromatography.
Clone No: 3F1E3.
Isotype: IgG1.
Storage/Stability: Stable for 1 year at -20°C and 3 months at -20°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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