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Conditions of optimal HSD11B1 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Background
11?-hydroxysteroid dehydrogenase type 1 is an NADPH-dependent enzyme highly expressed in key metabolic tissues including liver, adipose tissue, and the central nervous system.In these tissues, HSD11B1 reduces cortisone to the active hormone cortisol that activates glucocorticoid receptors.It is inhibited by carbenoxolone, a drug typically used in the treatment of peptic ulcersTannin et al. (1991) localized the HSD11B1 gene to chromosome 1. The localization was confirmed by isolating the gene from a chromosome 1-specific library using the cDNA as a probe. Schutte et al. (2000) mapped the HSD11B1 gene to 1q32-q41.
PA003991-PA1372: HSD11B1 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human, rat, mouse. No cross reactivity with other proteins.
Applications: WB 1 ug/ml, IHC-P 1 ug/ml, IHC-F 1 ug/ml, ICC 1 ug/ml.
Reactivity: Human, Rat, Mouse.
Immunogen: A synthetic peptide corresponding to a sequence at the middle region of human HSD11B1 (131-145 aa), different from the mouse sequence by two amino acids.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Other HSD11B1 Antibody:
HSD11B1 Polyclonal Antibody
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