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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal HLA-DRB5 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
HLA class II histocompatibility antigen, DR beta 5 chain, also known as DR beta-5, DR2-beta-2, Dw2, MHC class II antigen DRB5, HLA-DRB5, is a single-pass type I membrane protein which belongs to the MHC class II family. HLA-DRB5 contains one Ig-like C1-type domain. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. HLA-DRB5 plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells. Within the DR molecule, the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. The presence of DRB5 is linked with allelic variants of DRB1, otherwise it is omitted.
BP001421-CA75: Recombinant Human HLA-DRB5 (HLA class II histocompatibility antigen)
Source: HEK 293 derived.
Purity > 95%, by reducing SDS-PAGE and SEC-HPLC.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
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