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Conditions of optimal HDAC6 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Description
Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from an E-N-acetyl lysine amino acid on a histone or other proteins. Its action is opposite to that of histone acetyltransferase. HDAC proteins are found in three groups, the first two groups belong to the classical HDACs and their activities are inhibited by trichostatin A (TSA) whereas the third group is a family of NAD+-dependent proteins not affected by TSA. Homologues to all three groups are found in yeast having the names reduced potassium dependency 3 (Rpd3) -corresponds to class 1, histone deacetylase 1 (hda1) ? to class 2 and silent information regulator 2(Sir2) ? class3 Affinity purified rabbit polyclonal anti-HDAC11 antibody is developed with c-terminal peptide of human histone deacetylase 6. It could be used for detection and isolation of HDAC 6.
PA000578-C0226: HDAC6 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: HDAC6 antibody detects endogenous levels of total HDAC6 protein.
Applications: WB: 1:300~1:1000 IHC: 1:50~1:100 ELISA: 1:5000.
Reactivity: Human, Mouse.
Immunogen: The antiserum was produced against synthesized peptide derived from human HDAC6.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form of Antibody: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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