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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal GRP Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
U6 snRNA-associated Sm-like protein LSm4, also known as Glycine-rich protein, GRP, LSM4, is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif and are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSM4 forms a heteromer with a donut shape. The complexes are involved in various steps of RNA metabolism. LSM4 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM4 contributes RNA protein interactions and structural changes which are essential during ribosomal subunit assembly.
BP001434-C230: Recombinant Human Glycine-rich protein (GRP) Protein
Source: E. coli-derived.
Recombinant Human Glycine-rich protein (GRP) Protein is expressed with sequence (Met1-Gln139) of Human LSM4 fused with a His tag at the C-terminus.
Purity: > 95% by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, pH8.0.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other GRP Proteins:
Recombinant Human GRP Protein
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