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Conditions of optimal GPR56 Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
G-protein coupled receptor 56, also known as Protein TM7XN1, TM7LN4, TM7XN1 and GPR56, is a multi-pass membrane protein which belongs to the G-protein coupled receptor 2 family of LN-TM7 subfamily. GPR56 contains seven transmembrane domains and a mucin-like domain in the N-terminal region. GPR56 is widely distributed, with highest levels found in thyroid gland, brain and heart. It is also expressed in a great number of tumor cells. GPR56 could be involved in cell-cell interactions. GPR56 is implicated in the regulation of brain cortical patterning. It binds specifically to transglutaminase 2 in the extracellular space. Its expression is down-regulated in melanoma cell lines, and over-expression of GPR56 can suppress tumor growth and metastasis. Mutations in GPR56 result in bilateral frontoparietal polymicrogyria.
BP001415-CA72: Recombinant Human GPR56 (G-protein coupled receptor 56)
Source: HEK 293 derived.
Purity > 95%, by reducing SDS-PAGE and SEC-HPLC.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
GPR56 Antibodies:
GPR56 Polyclonal Antibody
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