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Home > Proteins & Peptides > A-Z Proteins  > Galectin-7 Protein

Galectin-7 Protein

Gal-7, HKL-14, PI7, p53-induced gene 1 protein, LGALS7, PIG1, LGALS7B, GAL7, LGALS7A

Catalog No. Product Name Size List Price (US$) Quantity
BP000199-C069 Recombinant Human Galectin-7 50 ug 264.00
BP000199-C069 Recombinant Human Galectin-7 1 mg 2640.00
Description

Introduction
Galectins are a family of animal lectins with an affinity for beta-galactosides. This family has at least 14 identified members. Galectins share similarities in the CRD (the carbohydrate recognition domain). Galectins are synthesized as cytosolic proteins. Though localized principally in the cytoplasm and lacking a classical signal peptide, galectins can also be stimulated to secretion by non-classical pathways or alternatively targeted to the nucleus. Galectins are involved in modulating cell-cell and cell-matrix interactions. Human Galectin-7 belongs to the prototypical Galectins containing a single CRD, which is initially identified in human epidermis as a monomer. The Galectin-7 expression is induced by tumor suppressor protein p53 and associated with apoptosis. Galectin-7 is a pro-apoptotic protein which functions intracellularlly upstream of JNK activation and mitochondrial cytochrome c release. The correlation of Galectin-7 with the UV-induced apoptosis of keratinocytes presents a critical mechanism in the maintenance of epidermal homeostasis. Human Galectin-7 is localized in both nucleus and cytoplasm.

BP000199-C069: Recombinant Human Galectin-7

Source: E. coli-derived.
Purity > 95%, by reducing SDS-PAGE and SEC-HPLC.
Formulation: Lyophilized at 1 ug/ml in 20 mM PBS.
Reconstitution: It is recommended to reconstitute the lyophilized Recombinant Human Galectin 7 in PBS not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other Galectin-7 Proteins:
Recombinant Human Galectin-7
Recombinant Human Galectin-7

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