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G-CSF Protein

Granulocyte colony-stimulating factor, Pluripoietin, Filgrastim, Lenograstim, CSF3, C17orf33, GCSF
Catalog No. Product Name Size List Price (US$) Quantity
BP000175-C028 Recombinant Human PEG-G-CSF Protein 10 ug 126.00
BP000175-C028 Recombinant Human PEG-G-CSF Protein 50 ug 378.00
BP000175-C028 Recombinant Human PEG-G-CSF Protein 1 mg 2640.00
Description

Introduction
Human Granulocyte-Colony-Stimulating Factor (G-CSF) is 20 kD glycoprotein containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and it functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, Interleukin-1, and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF. In epithelial, endothelial, and fibroblastic cells secretion of G-CSF is induced by Interleukin-17.

BP000175-C028: Recombinant Human Granulocyte colony-stimulating factor (G-CSF) Protein

Source: E. coli-derived.
Recombinant Human Granulocyte colony-stimulating factor (G-CSF) Protein is a single non-glycosylated polypeptide chain containing 175 amino acids with a molecular mass of 18,800 Daltons.
Predicted molecular mass: 38,800 Dalton.
The ED50, calculated by the dose-dependant proliferation of murine NFS-60 indicator cells is less then 0.1 ug/ml, corresponding to a Specific Activity of 1.0 x 107 IU/mg.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 um filtered solution of 10 mM HAc-NaAc, 150 mM NaCl, 0.004% tween80, 5% mannitol, pH4.0.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution

Other G-CSF Proteins:
Recombinant Mouse G-CSF Protein
Recombinant Human Pegylated G-CSF Protein
Recombinant Human PEG-G-CSF Protein
Recombinant Human G-CSF Protein, His Tag
Recombinant Human G-CSF Protein, HEK
Recombinant Human G-CSF Protein, CHO
Recombinant Human G-CSF Protein
Recombinant Human G-CSF Protein
Recombinant Human G-CSF Protein

G-CSFR Antibodies:
G-CSF Monoclonal Antibody
FITC Conjugated G-CSF Monoclonal Antibody
Biotin Conjugated G-CSF Monoclonal Antibody

G-CSF ELISA Kits:
Mouse G-csf ELISA Kit
Human G-CSF ELISA Kit

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