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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal FGG Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Introduction
Fibrinogen gamma Chain (FGG) contains two sets of three non-identical chains and a long coiled coil structure connected to the central nodule to the C-terminal domains. The long C-terminal ends of the alpha chains fold back to contributing a fourth strand to the coiled coil structure. Defects in FGG lead to Congenital Afibrinogenemia (CAFBN). CAFBN is a rare autosomal recessive disorder characterized by bleeding that varies from mild to severe and by the complete absence or extremely low levels of plasma and platelet fibrinogen. Patients with congenital fibrinogen abnormalities can manifest different clinical sympotoms, including a tendency toward bleeding, clinically silent and predisposition for thrombosis, with or without bleeding.
BP001502-C609: Recombinant Human Fibrinogen gamma Chain (FGG) Protein
Source: E. coli derived.
Recombinant Human Fibrinogen gamma Chain (FGG) Protein is expressed with sequence (M1-D130) of Human FGG fused with a polyhistidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
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