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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal FCRL1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Fc receptor-like protein 1, also named FcR-like protein 1, FcRL1, Fc receptor homolog 1, FcRH1, IFGP family protein 1, hIFGP1 and Immune receptor translocation-associated protein 5, is a single-pass type I membrane protein which may function as an activating coreceptor in B cells. FcRH1 primarily expressed in secondary lymphoid tissues by mature subsets of B cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level). FcRH1 contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs and may play a role in the regulation of cancer cell growth.
BP001447-C607: Recombinant Human Fc receptor-like protein 1 (FCRL1)
Source: HEK 293-derived.
Recombinant Human Fc receptor-like protein 1 (FCRL1) is expressed with sequence (Ala17-Asn303) of Human FCRL1 fused with a polyhistidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PBS, 150 mM NaCl, 1 mM EDTA, pH7.4.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
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