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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal human Fc gamma RIIIB protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background
Human Fc gamma RIIIB, also known as CD16b, is a receptor of the Fc region of immunoglobulin γ. This receptor acts late in the immune response by binding with low affinity and recognizing IgG as aggregates surrounding multivalent antigens. Human Fc gamma RIIIB is found on neutrophils as well as stimulated eosinphils and acts to trap immune complexes in the peripheral circulation.
BP4100: Recombinant human Fc gamma RIIIB protein
Source: HEK 293 cell-derived.
Recombinant human Fc gamma RIIIB protein is the full length Fc gamma RIIIB protein fused with a polyhistidine tag at the C-terminus.
Purity: >95% by SDS-PAGE under reducing conditions.
Activity: Recombinant human Fc gamma RIIIB protein binds to human IgG as a low affinity receptor.
Formulation: 0.2 μM filtered solution of 20 mM Hepes, 150 mM NaCl, pH 7.5.
Endotoxin Level: Less than 1 EU/ug of protein as determined by LAL method.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
1 month from date of receipt, 2 to 8°C as supplied.
3 months from date of receipt, -20°C to -70°C as supplied.
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