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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal human Fc gamma RIIIA (F158) protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background
Human Fc gamma RIIIA, also known as CD16a, binds the Fc region of IgG. This receptor acts late in the immune
response by binding with low affinity and recognizing IgG as aggregates surrounding multivalent antigens. Human
Fc gamma RIIIA is commonly found on Natural Killer cells, macrophages, subpopulations of T-cells, immature
thymocytes, and placental trophoblasts and works to moderate antibody dependent cytotoxicity (ADCC) and
phagocytosis.
BP4098: Recombinant human Fc gamma RIIIA (F158) protein
Source: HEK 293 cell-derived.
Recombinant human Fc gamma RIIIA (F158) protein is the full length Fc gamma RIIIA (F158) protein fused with a polyhistidine tag at the C-terminus.
Purity: >95% by SDS-PAGE under reducing conditions.
Activity: Recombinant human Fc gamma RIIIA (F158) protein binds to human IgG as a low affinity receptor.
Formulation: 0.2 μM filtered solution of 20 mM Hepes, 150 mM NaCl, pH 7.5.
Endotoxin Level: Less than 1 EU/ug of protein as determined by LAL method.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
1 month from date of receipt, 2 to 8°C as supplied.
3 months from date of receipt, -20°C to -70°C as supplied.
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