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Background Information:
Epacadostat (INCB24360, INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM, highly selective over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). Displays potent in vitro and in vivo immunomodulating and antineoplastic activities. Currently in clinical trials.
Reference:
1. * To date (06/25/2015) all other vendors (no exception) offer this compound (INCB24360, INCB024360) with a wrong structure (with CAS No: 914471-09-3, Mol. Formula: C9H7ClFN5O2, Mol. Wt: 271.6). Buyer beware.
APIM050367: EPACADOSTAT
CAS No.: 1204669-58-8.
Molecular Formula: C11H13BrFN7O4S.
Molecular Weight: 438.2.
Purity: >99.5% (HPLC).
QC: HPLC-MS, 1HNMR, and Quantitative Elemental Analysis.
Solubility: SSee Solubility Data in COA.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
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