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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal Cytochrome P450 2D6 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Background
Cytochrome P450 2D6 (CYP2D6) is one of the most important enzymes involved in the metabolism of xenobiotics in the body. It is a member of Cytochrome P450, family 2, subfamily D, polypeptide 6. Its gene is mapped to chromosome 22q13.1. It has got 497 amino acid proteins which shares 73% sequence identity with the rat protein. CYP2D6 is highly expressed in human liver. CYP2D6 is the major isozyme involved in the formation of N-hydroxyprocainamide, a metabolite potentially involved in the drug-induced lupus syndrome observed with procainamide.
PA001388-PA1397: CYP2D6 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Rat, mouse. No cross reactivity with other proteins.
Applications: WB 0.1-0.5 ug/ml IHC-P 0.5-1 ug/ml.
Reactivity: Mouse, Rat.
Immunogen: A synthetic peptide corresponding to a sequence at the middle region of human CYP2D6, identical to the related mouse and rat sequence.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at 20 °C and 3 months at 4 °C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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