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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal CTSD Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Cathepsin D is synthesized as a 54 kDa precursor, which is proteolytically processed to an intermediate 48 kDa single chain, which matures into more stable 34 kDa and 14 kDa two chain form. It is an estrogen-regulated lysosomal protease that has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix, and xonnective tissue. Because of its mitogenic and proteolytic activities, it has been implicated as a prognostic marker in many tumor types. Cathepsin D is expressed in epithelial cells as well as in macrophages.
BP000753-C399: Recombinant Human Cathepsin D (CTSD) Protein
Source: HEK 293-derived.
Recombinant Human Cathepsin D (CTSD) Protein is expressed with the full length sequence of Human CTSD fused with a polyhistidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: 0.2 um filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other CTSD Proteins:
Recombinant Human CTSD Protein
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