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CRADD Protein

Death Domain-Containing Protein CRADD, RIP-Associated Protein with A Death Domain, RAIDD

Catalog No. Product Name Size List Price (US$) Quantity
BP002621-CF64 Recombinant Human CRADD Protein 10 ug 180.00
BP002621-CF64 Recombinant Human CRADD Protein 50 ug 528.00
BP002621-CF64 Recombinant Human CRADD Protein 1 mg 2880.00
Description

Introduction
Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.

BP002621-CF64: Recombinant Human Death Domain-Containing Protein CRADD (CRADD)

Source: E. coli-derived.
Recombinant Human Death Domain-Containing Protein CRADD (CRADD) is expressed with sequence (Met1-Glu199) of Human CRADD.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: 0.2 um filtered solution of PBS, pH 7.4.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

Other CRADD Proteins:
Recombinant Human CRADD Protein

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