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CLIC5 Protein

Chloride Intracellular Channel Protein 5

Catalog No. Product Name Size List Price (US$) Quantity
BP001748-C212 Recombinant Human CLIC5 Protein 10 ug 180.00
BP001748-C212 Recombinant Human CLIC5 Protein 50 ug 528.00
BP001748-C212 Recombinant Human CLIC5 Protein 1 mg 2640.00
Description

Introduction
Chloride Intracellular Channel Protein 5 (CLIC5) is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain. Chloride intracellular channels are involved in chloride ion transport within various subcellular compartments. CLIC5 can insert into membranes and form selective ion channels regulated by actin that may transport chloride ions. It may play a role in the regulation of transepithelial ion absorption and secretion. CLIC5 specifically associates with the cytoskeleton of placenta microvilli. CLIC5 is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture.

BP001748-C212: Recombinant Human Chloride Intracellular Channel Protein 5 (CLIC5) Protein

Source: E. coli-derived.
Recombinant Human Chloride Intracellular Channel Protein 5 (CLIC5) Protein is expressed with sequence (Met1-Ser251) of Human CLIC5 fused with a His tag at the C-terminus.
Purity: > 95% by reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

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