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Conditions of optimal CDK6 Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Cyclin-Dependent Kinase 6 (CDK6 belongs to the CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily. CDK6 is expressed in many tissues and contains one protein kinase domain. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. Mutations and overexpression of CDK6, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
BP002602-CF11: Recombinant Human Cyclin-Dependent Kinase 6 (CDK6) Enzyme
Source: E. coli-derived.
Recombinant Human Cyclin-Dependent Kinase 6 (CDK6) Enzyme is expressed with sequence (Met1-Ala326) of Human CDK6 fused with a 6His tag at the N-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: 0.2 um filtered solution of 50 mM Tris, 100 mM NaCl, 20% Glycerol, 5 mM DTT, pH 8.0.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
CDK6 Antibodies:
CDK6 Monoclonal Antibody
CDK6 (Ab-24) Polyclonal Antibody
CDK6 (Ab-24) Polyclonal Antibody
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