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CDK6 Enzyme

Cyclin-Dependent Kinase 6, Cell Division Protein Kinase 6, Serine/Threonine-Protein Kinase PLSTIRE, CDKN6

Catalog No. Product Name Size List Price (US$) Quantity
BP002602-CF11 Recombinant Human CDK6 Enzyme 10 ug 180.00
BP002602-CF11 Recombinant Human CDK6 Enzyme 50 ug 528.00
BP002602-CF11 Recombinant Human CDK6 Enzyme 1 mg 2880.00
Description

Introduction
Cyclin-Dependent Kinase 6 (CDK6 belongs to the CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily. CDK6 is expressed in many tissues and contains one protein kinase domain. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. Mutations and overexpression of CDK6, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.

BP002602-CF11: Recombinant Human Cyclin-Dependent Kinase 6 (CDK6) Enzyme

Source: E. coli-derived.
Recombinant Human Cyclin-Dependent Kinase 6 (CDK6) Enzyme is expressed with sequence (Met1-Ala326) of Human CDK6 fused with a 6His tag at the N-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: 0.2 um filtered solution of 50 mM Tris, 100 mM NaCl, 20% Glycerol, 5 mM DTT, pH 8.0.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

CDK6 Antibodies:
CDK6 Monoclonal Antibody
CDK6 (Ab-24) Polyclonal Antibody
CDK6 (Ab-24) Polyclonal Antibody

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