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CDC42 Antibody

Cell division control protein 42 homolog

Catalog No. Product Name Size List Price (US$) Quantity
PA005161-PA1366 CDC42 Polyclonal Antibody 100 ug 350.00
Description

Background
Cell division control protein 42 homolog also known as CDC42 is a protein involved in regulation of the cell cycle. In humans, CDC42 is encoded by the CDC42 gene.CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.

PA005161-PA1366: CDC42 Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human, rat, mouse, bovine. No cross reactivity with other proteins.
Applications: WB 1 ug/ml, IHC-P 1 ug/ml.
Reactivity: Human, Rat, Mouse, bovine.
Immunogen: A synthetic peptide corresponding to a sequence at the middle region of human CDC42 (121-138aa), identical to the related mouse and rat sequence
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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