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Conditions of optimal CA2 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Fax: 1-617-606-5019
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BACKGROUND
Carbonic anhydrase II (CA2), is one of fourteen forms of human ? Carbonic anhydrases. Carbonic anhydrases (CAs) are a family of zinc metalloenzymes. Using Southern blot analysis and restriction endonucleases, it is determined that the CA2 gene consists of 7 exons. Using a mouse CA II cDNA hybridization probe with a panel of mouse-human cell hybrids, The CA2 gene was assigned to human chromosome 8. CA2 is expressed at high levels in osteoclasts during bone resorption. It is demonstrated in 2 in vitro culture systems that antisense RNA and DNA blocked expression of CA2 and led to decreased bone resorption. In the choroid plexus, CA2 supports the transport of bicarbonate ions, sodium ions, and water from the blood to the cerebrospinal fluid.
PA004997-PA1438: CA2 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human, mouse, rat No cross reactivity with other proteins.
Applications: WB 1ug/ml.
Reactivity: Human, Mouse, Rat.
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human CA2, identical to the related mouse and rat sequences.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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