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Biotinylated Human Nectin-4 Protein

EDSS1; Ig superfamily receptor LNIR; Nectin-4; poliovirus receptor-related protein 4; PRR4; DKFZp686K05193; PVRL4

Catalog No. Product Name Size List Price (US$) Quantity
Description

BP003085: Biotinylated Recombinant Human Nectin-4 Protein

Source: biotinylated recombinant human Nectin-4 protein (Gly32-Val351) was expressed in mammalian cells with a His and Avi tag at the C-terminus.
Accession: Q96NY8
Predicted molecular mass: 57.4 kDa. Due to glycosylation, the biotinylated recombinant human Nectin-4 protein migrates to 75-105 kDa based on the Bis-Tris PAGE result.
Endotoxin: Less than 1 EU per ug by the LAL method.
Formulation: The biotinylated recombinant human Nectin-4 protein was lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.
Purity: > 95% by Bis-Tris PAGE and HPLC.

Shipping: The biotinylated recombinant human Nectin-4 protein is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Background

Nectin-4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.(Microbial infection) Acts as a receptor for measles virus.

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