Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Catalog No. | Product Name | Size | List Price (US$) | Quantity |
---|
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background Information:
BI6727 (Volasertib)is a highly potent, selective and ATP-competitive inhibitor of polo-like kinases 1 , 2 and 3 (PLK1, 2 and 3), with IC50s at 0.87, 5 and 56 nM, respectively.
Reference:
1. Rudolph, D., et al, BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity, Clin Cancer Res., May 1, 2009; 15 (9), 3094-3102.
2. K. Strebhardt, Nature Reviews Drug Discovery, 9, 643-660 (August 2010)* A product coming with an excellent quantitative elemental analysis, made for in vivo studies . In stock from Indianapolis. Ship within 1 day.
APIM050114: BI 6727 (VOLASERTIB)
CAS No.: 755038-65-4.
Molecular Formula: C34H50N8O3?0.5H2O.
Molecular Weight: 627.8.
Purity: 99% (HPLC at 214 and 254 nm), >99% optical purity (Chiral HPLC referenced to opposite enantiomer).
QC: HPLC-MS, 1HNMR and Quantitative Elemental Analysis.
Solubility: In DMSO, alcohols, water with 2 eq. of acid.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
Copyright © 2009-2022 sydlabs.com. All rights reserved.
Use of this website means that you have read, understood, and accepted the Syd Labs Privacy Policy and Terms & Conditions.