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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal BAX antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Background
BAX (Bcl-2 Associated X Protein) is a member of the Bcl-2 gene family, it encodes a 21-kDa protein whose association with Bcl-2 is believed to play a critical role in regulating apoptosis. Human BAX gene is located in the q13.3-q13.4 region of human chromosome 19. Bax is an apoptosis-inducing protein that participates in cell death during normal development and in various diseases. It resides in an inactive state in the cytosol of many cells. Bax consists of 9 alpha helices and has extensive amino acid homology with Bcl-2, focused within highly conserved domains I and II. Bax is encoded by six exons and demonstrates a complex pattern of alternative RNA splicing that predicts a 21 kd membrane (alpha) and two forms of cytosolic protein (beta and gamma). BAX and BAK are essential for regulating the number of B cells at both immature and mature developmental stages. They are critical mediators of B cell death induced by multiple stimuli.
PA000149-PA1013: BAX Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human, mouse, rat.No cross reactivity with other proteins.
Applications: Western blot: At 1-2 ug/ml with the appropriate system to detect BAX in cells and tissues.
Reactivity: Human, Mouse, Rat, Rabbit.
Immunogen: A synthetic peptide corresponding to a sequence mapping near the N-terminal of human BAX, different to the related rat and mouse sequence by a single amino acid.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Other BAX Antibodies:
BAX Polyclonal Antibody
BAX Polyclonal Antibody
BAX Polyclonal Antibody
Bax Polyclonal Antibody
Bax (Ab-184) Polyclonal Antibody
Bax (Ab-167) Polyclonal Antibody
BAX Protein:
Recombinant Human BAX Protein
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