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ASGPR1 Protein

Asialoglycoprotein receptor 1, Hepatic Lectin H1, HL-1, ASGR1, CLEC4H1, ASGP-R 1, ASGPR 1

Catalog No. Product Name Size List Price (US$) Quantity
BP001226-C428 Recombinant Human ASGPR1 Protein 10 ug 98.00
BP001226-C428 Recombinant Human ASGPR1 Protein 50 ug 264.00
BP001226-C428 Recombinant Human ASGPR1 Protein 1 mg 2640.00
Description

Introduction
Asialoglycoprotein Receptor 1 (ASGPR1) is an endocytic recycling receptor, belongs to the long-form subfamily of the C-type/Ca2+-dependent lectin family. ASGPR consists of two noncovalently-linked subnits, ASGPR1 and ASGPR2. ASGPR1 mediates the endocytosis of plasma glycoproteins, recognizes terminal galactose and N-acetylgalactosamine units. When the ligand binds to to ASGPR1, results in the complex is internalized and transported to a sorting organelle, then ASGPR1 and ligand can be disassociated, ASGPR1 returns to the cell membrane surface.

BP001226-C428: Recombinant Human Asialoglycoprotein Receptor 1 (ASGPR1) Protein

Source: HEK 293-derived.
Recombinant Human Asialoglycoprotein Receptor 1 (ASGPR1) Protein is a secreted protein with sequence (Gln62-Ile291) of Human ASGPR1 fused with a polyhistidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

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