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Conditions of optimal ANGPTL3 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Introduction
Angiopoietin-like proteins ANGPTL3 and ANGPTL4 are secreted proteins mainly expressed in liver that have been demonstrated to regulate triglyceride metabolism by inhibiting the lipolysis of triglyceride-rich lipoproteins. ANGPTL3 is structurally similar to angiopoietins, which are vascular endothelial growth factors. The experimental results show that Angptl3 and Angptl4 function to regulate circulating triglyceride levels during different nutritional states and therefore play a role in lipid metabolism during feeding/fasting through differential inhibition of Lipoprotein lipase (LPL). Using deletion mutants of Angiopoietin 5 human, it was demonstrated that the N-terminal domain containing fragment -(17?07) and not the C-terminal fibrinogen-like domain containing fragment -(207?60) increased the plasma triglyceride levels in mice.
PA005196-PA2075: ANGPTL3 Polyclonal Antibody
Rabbit Polyclonal Antibody;
Applications: WB 0.1-0.5 ug/ml.
Reactivity: Human, Rat, Mouse;
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human ANGPTL3, identical to the related rat and mouse sequences.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Other ANGPTL3 Antibody:
ANGPTL3 Monoclonal Antibody
ANGPTL3 Protein:
Recombinant Human ANGPTL3
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