Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Catalog No. | Product Name | Size | List Price (US$) | Quantity |
---|
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background Information:
AG-221 (Enasidenib) is a first-in-class, orally available, selective, potent inhibitor of mutant IDH2 (Isocitrate dehydrogenase type 2). It specifically inhibits IDH2 in the mitochondria, blocking the formation of oncometabolite 2-hydroxyglutarate (2HG). In in vitro studies, AG-221 reduced 2-HG levels by >90%, reversed histone and DNA hypermethylation, and induced cellular differentiation in leukemia cell models.
APIM050312: AG-221 (ENASIDENIB)
CAS No.: 1446502-11-9.
Molecular Formula: C19H17F6N7O.
Molecular Weight: 473.4.
Purity: >99.5% by HPLC at 214 and 254 nm.
QC: HPLC-MS, 1H-NMR and Quantitative Elemental Analysis Report.
Solubility: Refer to Certificate.
Storage: Refer to Certificate.
Copyright © 2009-2022 sydlabs.com. All rights reserved.
Use of this website means that you have read, understood, and accepted the Syd Labs Privacy Policy and Terms & Conditions.