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Home > Chemicals > Amino Acids and Derivatives > AFURESERTIB (GSK2110183)

AFURESERTIB (GSK2110183)

GSK2110183

Catalog No. Product Name Size List Price (US$) Quantity
APIM050073 AFURESERTIB (GSK2110183) 5 mg 80.00
APIM050073 AFURESERTIB (GSK2110183) 10 mg 120.00
APIM050073 AFURESERTIB (GSK2110183) 50 mg 300.00
APIM050073 AFURESERTIB (GSK2110183) 100 mg 450.00
APIM050073 AFURESERTIB (GSK2110183) 200 mg 790.00
Description

Background Information:

Afuresertib (GSK2110183) is a cell-permeable, orally bioavailable, potent and selective ATP-competitive pan-AKT inhibitor with Ki at low nMs for all three iso-forms , currently in clinical evaluation for cancer treatment.

APIM050073: AFURESERTIB (GSK2110183)

CAS No.: 1047645-82-8 (HCl Salt) 1047644-62-1 (Free base).
Molecular Formula: C18H17Cl2FN4OS ? HCl.
Molecular Weight: 463.8.
Purity: 100% optical purity (chiral HPLC), >99.5% chemical purity (achiral HPLC at 214 and 254 nm).
QC: HPLC-MS, 1HNMR, Chiral HPLC, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO and Water.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.

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