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Background Information:
A potent and selective inhibitor of B-cell lymphoma-2 (BCL-2) family proteins.
Reference:
1. Oltersdorf, T., et al, An inhibitor of Bcl-2 family proteins induces regression of solid tumours, Nature, 435, 677-681, 2005.
2. Trudal, S., et al, The Bcl-2 family protein inhibitor, ABT-737, has substantial antimyeloma activity and shows synergistic effect with dexamethasone and melphalan, Clinical Cancer Research, 13, 621, January 15, 2007.
APIM050280: ABT-737
CAS No.: 852808-04-9.
Molecular Formula: C42H45ClN6O5S2.
Molecular Weight: 813.43.
Purity: >99% Chem and optical purity (HPLC and chiral HPLC).
QC: MS, 1HNMR, HPLC.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
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