Home Resources Resources Enzymes

Heparinases and their heparin-related applications

Heparin, a highly sulfated glycosaminoglycan with the highest negative charge density of any known biological molecule, is located in the extracellular matrix and plays important physiological roles in anticoagulation and angiogenesis. The acidic polysaccharide of heparin consists of a heterogeneous disaccharide repeating unit of hexosamine and uronic acid (L-iduronic or D-glucuronic acid) connected through 1-4 […]