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Panitumumab Biosimilar, EGFR Monoclonal Antibody

Anti-ErbB-1 Human Monoclonal Antibody, Anti-HER1 Human Monoclonal Antibody

Catalog No. Product Name Size List Price (US$) Quantity
C012P Panitumumab Biosimilar, Human EGFR/ErbB-1/HER1 Monoclonal Antibody 1 mg 175.00
C012P Panitumumab Biosimilar, Human EGFR/ErbB-1/HER1 Monoclonal Antibody 5 mg 600.00
C012P Panitumumab Biosimilar, Human EGFR/ErbB-1/HER1 Monoclonal Antibody 20 mg 1200.00
C012P.05 Panitumumab Biosimilar, Endotoxin 0.05 EU/mg 5 mg 900.00
C012P.05 Panitumumab Biosimilar, Endotoxin 0.05 EU/mg 20 mg 1800.00
C012P.LA Panitumumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant 1 mg 650.00
C012P.NA Panitumumab Biosimilar, N297A Mutant 1 mg 650.00
Description

C012P: Panitumumab Biosimilar, Human EGFR/ErbB-1/HER1 Monoclonal Antibody

Recombinant Humanized IgG2 Monoclonal Antibody.
Isotype: Human IgG2 kappa.
Source: The monoclonal antibody panitumumab biosimilar was produced in the Panitumumab biosimilar CHO stable cell line.
Specificity/Sensitivity: The monoclonal antibody panitumumab biosimilar specifically binds to the human EGFR, ErbB-1 and HER1.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by panitumumab.
Form of Antibody: 0.2 uM filtered solution, pH 6.0, no stabilizers or preservatives.
Endotoxin: < 1 EU per 1 mg of the protein by the LAL method.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.

Shipping: The monoclonal antibody panitumumab is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month from date of receipt, 2 to 8°C as supplied.

Background

Panitumumab, a fully anti-EGFR (epidermal growth factor receptor, EGF receptor, ErbB-1 and HER1 in humans) human monoclonal antibody, is used for the treatment of refractory EGFR-expressing metastatic colorectal cancer in patients with non-mutated (wild-type) KRAS".

Syd Labs also provides the following anti-ErbB/HER antibody biosimilar stable cell lines:
Cetuximab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Trastuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Pertuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)

Syd Labs also provides the following research grade antibody biosimilar proteins:
Bevacizumab Biosimilar, research grade (VEGF-A)
Ranibizumab Biosimilar, research grade (VEGF-A, Fab produced in E. coli)
Cetuximab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Panitumumab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Trastuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Pertuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Infliximab biosimilar, research grade (TNF alpha)
Adalimumab biosimilar, research grade (TNF alpha)
Rituximab biosimilar, research grade (CD20)
Denosumab biosimilar, research grade (RANKL, RANK ligand, OPGL, TNFSF11, CD254, TRANCE, ODF)
Palivizumab Biosimilar, research grade (RSV)
Omalizumab biosimilar, research grade (IgE)
Eculizumab biosimilar, research grade (C5)

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