Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
|---|
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background Information:
GS-9901 is an orally active, potent and isoform-selective inhibitor of PI3Kδ (PI3Kδ IC50 = 1.0 nM, HWB δ EC50 = 1.5 nM; CLpr hHep = 0.05 L/h/kg.), and a potential immunomodulating agent. It is highly selective against other isoforms: p110α (750 nM), p110β (100 nM) and P110γ (190 nM) (ref. 1). It is currently in clinical development for the treatment of hematological malignancies.
Reference:
1. L. Patel, et al, Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic Stability. J. Med. Chem. 2016, 59, 9228−9242.
APIM050034: GS-9901
CAS No.: 1640247-87-5.
Molecular Formula: C22H17ClFN9O.
Molecular Weight: 477.9 (or refer to Certificate of Analysis, batch-specific).
Purity: >99.5% chem and optical purity.
QC: HPLC-MS, 1H-NMR, Chiral HPLC and Quantitative Elemental Analysis Report.
Solubility: refer to certificate of analysis.
Storage: refer to certificate of analysis.
Copyright © 2009-2022 sydlabs.com. All rights reserved.
Use of this website means that you have read, understood, and accepted the Syd Labs Privacy Policy and Terms & Conditions.