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Background Information:
DS-3032 (Milademetan) is an orally available, potent and selective inhibitor of the p53-MDM2 (murine double minute 2) interaction. It is currently being evaluated in three phase 1 clinical trials for solid and hematological malignancies, including acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML) in blast phase, lymphoma and myelodysplastic syndrome (MDS).
APIM050033: DS-3032 (Milademetan)
CAS No.: 1398568-47-2.
Molecular Formula: C30H34Cl2FN5O4.
Molecular Weight: 618.5 (refer to Certificate of Analysis, batch specific).
Purity: 99% by Achiral and Chiral HPLCs.
QC: HPLC-MS, Chiral HPLC, 1HNMR and Quantitative Elemental Analysis Report.
Solubility: refer to Certificate of Analysis.
Storage: refer to Certificate of Analysis.
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