Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Catalog No. | Product Name | Size | List Price (US$) | Quantity |
---|
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background Information:
ADU-S100 (MIW815) is a synthetic cyclic dinucleotide (CDN) agonist (activator) of Stimulator of Interferon Genes (STING), a receptor crucial to activate the innate (endogenous) immune system. ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression of cytokines and chemokines, leading to a robust and durable antigen-specific T-cell mediated immune response against cancer cells (ref. 1).
Reference:
1. Corrales L et al., 2015. Direct activation of STING in the tumor microenvironment leads to potent and systemic tumor regression and immunity. Cell Rep. 11(7):1018-30.
*Water soluble (>73.5mg/ml, >100 mM). 1.0 mg in 1.0 ml water = 1.36 mM.
APIM050006: ADU-S100 (MIW815)
CAS No.: 1638750-95-4 (Sodium Salt), 1638241-89-0 (Free Acid)
Molecular Formula: C20H22N10O10P2S2?2Na
Molecular Weight: 734.5
Purity: >99.5% by HPLC (at 214 nm).
QC: HPLC, MS, 1H-, 31P-NMRs,
Solubility: Water (>36.7mg/ml, >50 mM).
Storage: refer to Certificate of Analysis.
Copyright © 2009-2022 sydlabs.com. All rights reserved.
Use of this website means that you have read, understood, and accepted the Syd Labs Privacy Policy and Terms & Conditions.