Our FcRγ binding assay and FcRn binding assay services include: his-tagged receptors are immobilized onto anti-His biosensors; the loaded biosensors are dipped into a dilution series of the antibody; the on- (Kon) and off-rates (Koff) are measured and the KD value is calculated.
Syd Labs screens scFv phage libraries using several different formats for applications including de novo antibody discovery and affinity maturation of existing antibodies.
Syd Labs generates scFv phage libraries from immunized or naive donors from several species. Additionally, various mutagenesis strategies can be used to design scFv phage libraries for affinity maturation of a given antibody or other optimization purposes. Our scFv phage library is generated with a goal of up to 1010 clones and quality controlled by sequencing 96 clones at random.
Our epitope binning service include: Antigen is immobilized onto a biolayer interferometry (BLI) sensor using an appropriate method. Antibody 1 is allowed to saturate its epitope on the antigen. Binding of Antibody 2 to antigen saturated with Antibody 1 is assessed.
Fast turnaround: 2-3 weeks.
- Any gene;
- Any host cell, including primary cell;
- Highly efficient and precise.
Fast turnaround:
Knock-out cell line generation: 16-19 weeks.
Knock-in cell line generation: 20-24 weeks.Our adenovirus production services for toxic genes include: 1) construction of an adenovirus vector for expression of a cytotoxic gene; 2) generation of adenoviruses carrying cytotoxic genes; 3) amplification and purification of adenoviruses carrying cytotoxic genes.
Our adenovirus production team has constructed, amplified, and purified thousands of adenoviruses for worldwide clients in more than a decade. An improved technology is used to simplify and accelerate construction of adenoviral vectors for researchers studying gene expression or gene silencing in mammalian systems.
Fast turnaround: 2 weeks.Our Ad5-RGD and Ad5/35 adenovirus production services include: 1) construction of an Ad5-RGD and Ad5/35 adenovirus vector for expression or silencing of a gene; 2) generation of Ad5-RGD and Ad5/35 adenovirus; 3) amplification and purification of Ad5-RGD and Ad5/35 adenovirus.
Our adenovirus production team has constructed, amplified, and purified thousands of adenoviruses for worldwide clients in more than a decade. An improved technology is used to simplify and accelerate construction of adenoviral vectors for researchers studying gene expression or gene silencing in mammalian systems.
Fast turnaround: 2 weeks.Syd Labs provides comprehensive virus titer test services: Multiplicity of Infection (MOI) assay, 50% Tissue Culture Infective Dose (TCID50), Replication-Competent Adenovirus (RCA) assays with PCR and A549 cells, and plaque assay with Plaque Forming Units (PFU).
Custom peptide synthesis service with guaranteed high quality and fast delivery.
Starting from $1.80 per amino acid.
High success rate: >98%.
Various purity levels: crude, desalted, >75%, >85%, >90%, >95%, >98%, and even above 99%.
Various scales from milligrams to kilograms.
Various peptide length: up to 200 amino acids.
Free aliquoting up to 5 vials.
Fast turnaround time: 2-3 weeks.
Large scale (>1 gram), Long sequence (>50mer), unusual, and difficult peptides are available upon request.
Free consulting services for selecting antigen specificity for polyclonal and monoclonal antibody production.Custom peptide synthesis service with guaranteed high quality and fast delivery.
Starting from $1.80 per amino acid.
Peptide acetylation / amidation / methylation / phosphorylation.
Fluorescein / Biotin labeled peptides.
Cyclic peptides.
MAP peptides.
High success rate: >98%.
Various purity levels: crude, desalted, >75%, >85%, >90%, >95%, >98%, and even above 99%.
Various scales from milligrams to kilograms.
Various peptide length: up to 200 amino acids.
Free aliquoting up to 5 vials.
2-3 weeks of turnaround time.
Large scale (>1 gram), Long sequence (>50mer), unusual, and difficult peptides are available upon request.
Free consulting services for selecting antigen specificity for polyclonal and monoclonal antibody production. A lot of experience with antibody development using modified peptides, such as phosphopeptides.