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The manufacturing conditions of Orencia biosimilar from the CHO stable cell line need to be optimized by clients.
Syd Labs does not sell Orencia biosimilar as a drug in any country or area.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Abatacept (trade name Orencia, Bristol-Myers-Squibb), a fusion protein of a Fc fragment (human IgG1 isotype) and the extracellular domain of CTLA-4, can be used to extend graft survival while limiting the toxicity generated by standard immune suppressing regimens, such as calcineurin inhibitors. Abatacept binds to CD80 (B7-1) with more avidity than to CD86 (B7-2). Abatacept inhibits the costimulation of T cells. Abatacept differs from belatacept (trade name Nulojix) by only 2 amino acids.
The CTLA-4 protein is important for T-cell costimulation and selectively blocks the process of T-cell activation.
C007: Orencia Biosimilar Stable Cell Line (CHO)
The yield of Orencia biosimilar from the CHO stable cell line was above 2.1 g/L in a 15 liter manufacturing.
The Orencia biosimilar stable cell line alone can be transferred alone or together with the technology of process development and/or antibody purification.
Syd Labs also provides the following CTLA-4 Fc Fusion Protein biosimilar stable cell line:
Nulojix Biosimilar Stable Cell Line
Recombinant PD1 Protein:
Recombinant Human PD1-Fc Fusion Protein (IgG1)
Recombinant Human PD1-His Fusion Protein
Recombinant PDL1 Protein:
Recombinant Human PDL1-Fc Fusion Protein (IgG1)
Recombinant Human PDL1-FLAG Fusion Protein
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